Radioisotope Production (Fluorine-18)

F-18 decays by positron emission with a short half-life of approximately 110 minutes. It is typically produced in cyclotrons by bombarding enriched oxygen-18 with protons. The resulting F-18 is then chemically incorporated into radiopharmaceuticals, such as FDG (fluorodeoxyglucose). Supply chain considerations involve the availability of cyclotrons, enriched oxygen-18, and specialised radiochemistry facilities. Logistical challenges include the rapid transport and delivery of F-18 radiopharmaceuticals due to their short half-life. Accessibility for developing countries is limited by the high cost and technical expertise required for production and handling.

F-18 production and application are well-established, with widespread use in nuclear medicine.

F-18 is a radioactive isotope that emits positrons and gamma rays, requiring careful handling and shielding to minimise radiation exposure. The short half-life necessitates rapid processing and delivery.

While F-18 is not a proliferation concern, proper control and monitoring are necessary to prevent unauthorised access or misuse.

Traditional IAEA safeguards are not directly applicable due to the absence of fissile materials. However, monitoring and verification of the production and use of F-18 may be considered to ensure transparency and prevent misuse.